Przezroczysta folia PVDC: przełom w opakowaniach typu blister dla produktów farmaceutycznych
Materiał: ROLKA PVDC
Grubość 0,45-0,018 mm-dostosowanie
Rozmiar: 80MM/130MM/Dostosowanie
GATUNEK: folia o jakości farmaceutycznej
kolor: biały/personalizacja
lokalizacja: Chiny
Zastosowanie: Farmaceutyka, żywność suszona
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Transparent PVDC Film: A Breakthrough in Pharmaceutical Blister Packaging
I. Introduction
One of the major concerns of the pharmaceutical industry is the safety and uncompromised condition of the drugs. Various packaging for drugs protect them from moisture, oxygen, and microbial contamination among others. In the packaging of drugs, a quite effective material that has been used particularly in blister packaging is transparent PVDC film. This film possesses some distinctive properties that make it especially suitable for pharmaceutical applications.
II Properties of Transparent PVDC Film
A. Physical and mechanical properties
Strength and durability
PVDC film is a high tensile strength material that is both tear and puncture resistant. This resilience to the rigors of handling during packaging and transportation makes it very useful in certain applications. For example, in packaging sensitive pills, the film protects them from damage occasioned by rough handling.
Another reason for the toughness of the film is that it is abrasion resistant. In this regard, the film is suitable for applications where friction or rubbing should be applied to the film, for example, in the manufacturing of pharmaceutical
Multi-layer blister films based on PVC are often used for pharmaceutical blister packaging, whereby the PVC serves as the
thermoformable backbone of the structure. PVC layer can be colored with pigments and/or UV filters. Polyvinylidene chloride (PVDC)-coated PVC
| Product Name | Plastic Blister Packing Film, Pharma-grade PVC/PVDC Coated Film, Rigid PVC Film For Blister Pack |
| Color | Transparent ,White |
| Thickness | 0.25mm/40g or customized |
| PVDC Coating | 40gsm /60gsm /90gsm |
| Width | 50-1600mm |
| Inner Core Diameter | 76mm |
| MOQ | 1 ton |
| Certificate | ISO 9001,ISO 14001,GMP |
| Advantage | 1. High transparency, bright surface luminance. 2. Smooth surface, uniform thickness. 3. Few hydrological veins, few crystal points. 4. No smell and non-toxic. 5. Anti-cold 6. Can easily be thermoformed, printed, and folded |
Flexibility
The transparent PVDC film is very flexible; hence, it can be easily molded and shaped. It can be molded into different shapes, like blister packs, to accommodate different types of drugs. This also allows the material to take the contours of the product for a snug fit.
The film flexibility allows for easy folding and sealing of the pack hence a snug package. It can be used to create tamper - evidence seals which are important in preventing unauthorized access to the medication.
B. Chemical and barrier properties
Barrier against moisture
PVDC film has high resistance to moisture. Water vapor cannot permeate the film, and for that reason, it will keep the drug dry and protected. It is very important in drugs that are sensitive to moisture-for example, tablets and capsules.
The moisture barrier also contributes to the drug's shelf life by reducing the rate of moisture absorption. In the case of pharmaceutical products, the film can inhibit mold and bacteria growth that may be present due to moisture.
Gas and oxygen barrier
PVDC is a film that has very high barriers to gases and oxygen. It prevents the passing of oxygen, which may cause oxidation of drugs. Drugs that are sensitive to oxygen, like vitamins and antibiotics, depend on it.
The gas barrier property also provides integrity to the drug by preventing the release of volatile substances. For instance, it may prevent the loss of flavor and aroma of the drug.
Chemical resistance
The film is resistant to a wide range of chemicals, including acids, alkali, and solvents. This makes it suitable for use in pharmaceutical packaging, where it may come into contact with different substances.
Sterilization Methods: PVDC film withstands exposure to different methods of sterilization, including heat, radiation, and chemical disinfectants. It maintains sterility in packaging, hence ensuring the safety of drugs.
III Applications within the pharmaceutical industry
A. Blister packaging
Protection of tablets and capsules
The transparent PVDC film is widely used in blister packaging for tablets and capsules. The film acts as a barrier to moisture, oxygen, and other contaminants, protecting the drugs from degradation.
The high transparency of the film allows for easy viewing of the tablets or capsules, which is quite convenient for the patients to identify the medication. It also helps in preventing counterfeiting since the film can be easily inspected for signs of tampering.
For their integrality, PVDC film can be used to make a sealed environment surrounding the tablets or capsules. Blocking air and moisture ingressions can affect the quality of drugs.
Packaging of injectable drugs
In packaging injectable drugs, such as vials and syringes, PVDC film is also used. The barrier nature of the film against moisture and oxygen protects the drugs from contamination.
The flexibility of the film allows it to easily take the shape of the injectable device, securing and making the package leak-proof. A tamper-evident seal can also be made with it to make the drug safe.
The drug can be protected against photolytic degradation by using a PVDC film. Therefore, in the packaging of drugs susceptible to light, such as some vitamins and antibiotics.
B. Pharmaceutical packaging
Drug storage
PVDC film finds its application in the storage of drugs due to the hindrance of moisture and oxygen. The film is available for storing drugs under different environments such as hospitals and pharmaceutical firms.
The barrier properties of the film might reduce the rate of bacterial and other microorganism growths, further helping to extend the shelf lives of the drugs. Besides, it protects the drugs from moisture and oxygen that might cause its degradation.
The PVDC film can package drugs in retrievable and accessible forms. The PVDC film can be used for storage in an efficient and convenient method on the part of healthcare providers.
Drug delivery
PVDC film is used in drug delivery systems. Transdermal patches and inhalers use PVDC film. The film creates a barrier against moisture and oxygen to make the drug delivery system effective.
The flexibility in this film provides an easy way for it to be moulded on the drug delivery device in both a secure and effective method of delivery. The films can also be used to formulate such a drug delivery system and are customized according to patient needs.
The PVDC film can be used to administer drugs in a safe and efficient manner. It can thus be used to develop a drug delivery system that is convenient and easy to use. The maintenance of the device would also be relatively simple.
IV Challenges and future trends
A. Challenges
Cost - effectiveness
The cost of PVDC film is relatively high due to the cost of raw materials used and the manufacturing process that involves its production. However, the protection and performance benefits promoted by the film may overweight the cost in some certain cases.
The production of PVDC is expensive, thus the cost drives this film challenging to produce. Overcoming the challenge may need a finding of manufacturing process that will be used to decrease the production price or development of materials substitute materials that play a similar function with low priced.
Recyclability
The complicating structure makes the material of the film difficult to be recycled. The film consists of polymer and a layer of metal which is hardly separated by recyclers for recycling processes.
Because recycling technologies need to be developed which should be effective and at low costs. The manufacturers have to educate the consumers on the importance of recycling, which will encourage them to recycle PVDC film.
Environmental impact
The PVDC film may result in a great environmental impact concerning energy and resource use. The film may further be associated with greenhouse gas emission.
The manufacturing process should be sustainable and focused on the reduction of energy and resource use to minimize the impact on the environment. They should also employ ways of reducing greenhouse gas emissions.
B. Future trends
Development of new material
